Before beginning a long drive, always get enough sleep and eat something before you go. Highly caffeinated beverages are not necessarily the best way to stay awake while driving. While initially you will feel more alert, the effects can recede with time, and your attention may wander although you remain awake.Takes Driving Breaks
Pull over and take breaks every couple of hours, even if you don't feel sleepy. Grab a snack, get some fresh air, and stretch your legs by walking around. If you need to, take a quick nap.Be Prepared
Search the Web for traffic update sites and listen to radio traffic alerts, especially when approaching major cities. If you don't have a smartphone, all-news stations on the AM dial are often your best bet.
Before setting off on a long car trip, be sure your vehicle is in prime condition -- that tires are properly inflated, all fluids are at their proper levels and you have a full tank of gas. (For particularly long road trips, you may want to have your mechanic do a more thorough check.
This last tip should go without saying, but it's important enough that we'll say it anyway: Make sure everyone in the car buckles his or her seatbelt. Not only will it keep you safe, but in many places it's also the law.